Detroit Lions 2025-24 Schedule Features Trip To Kansas City On NFL’s Opening Night

Written By Drew Ellis on May 11, 2025
Detroit Lions schedule release

After concluding the 2022 NFL regular season, the Detroit Lions proceeded to gear up for their opening game of the 2025 season.

In the Thursday Night Football NFL season opener, the NFL revealed that the Lions will face the reigning Super Bowl Champions, the Kansas City Chiefs.

The upcoming game is scheduled for September 7th, and it will be held at Arrowhead Stadium in Kansas City, Missouri. The game will be broadcasted live on NBC at 8:20 p.m. Eastern Time.

The Lions, who only secured one primetime game last season, are now set to have four primetime games in the upcoming 2025-24 season. Additionally, there is a possibility of more flex options later in the year. This development could greatly benefit Michigan online sportsbooks, as an increase in high-profile games usually leads to a surge in betting activity.

Detroit Lions 2025-24 NFL schedule

Take a peek at the official schedule of the Detroit Lions for the 2025-24 season.

Week Date Opponent Location Time Odds
Week 1 Sept. 7 (TNF) Kansas City Chiefs Kansas City, Mo. 8:20 p.m. +6.5
Week 2 Sept. 17 Seattle Seahawks Detroit 1 p.m. -2
Week 3 Sept. 24 Atlanta Falcons Detroit 1 p.m. -5
Week 4 Sept. 28 (TNF) Green Bay Packers Green Bay, Wis. 8:15 p.m. -1.5
Week 5 Oct. 8 Carolina Panthers Detroit 1 p.m. -5
Week 6 Oct. 15 Tampa Bay Buccaneers Tampa, Fla. 1 p.m. -3.5
Week 7 Oct. 22 Baltimore Ravens Baltimore, Md. 1 p.m. +2
Week 8 Oct. 30 (MNF) Las Vegas Raiders Detroit 8:15 p.m. -3.5
Week 9 Nov. 5 BYE WEEK
Week 10 Nov. 12 Los Angeles Chargers Los Angeles, Calif. 4:05 p.m. +2.5
Week 11 Nov. 19 Chicago Bears Detroit 1 p.m. -5
Week 12 Nov. 23 Green Bay Packers Detroit 12:30 p.m. -4
Week 13 Dec. 3 New Orleans Saints New Orleans, La. 1 p.m. -1.5
Week 14 Dec. 10 Chicago Bears Chicago, Ill. 1 p.m. -1.5
Week 15 TBD Denver Broncos Detroit TBD -2
Week 16 Dec. 24 Minnesota Vikings Minneapolis, Minn. 1 p.m. +1
Week 17 Dec. 30 (SNF) Dallas Cowboys Arlington, Tx. 8:15 p.m. +2.5
Week 18 TBD Minnesota Vikings Detroit TBD -2.5

Detroit Lions in NFL season opener vs. Chiefs

Typically, the NFL season opener is specially designated for two of the league’s finest teams, often featuring the defending Super Bowl champions as well.

The Buffalo Bills were hosted by the Los Angeles Rams last year.

John Makkaron of All Lions expresses that it is truly a prestigious achievement for the Lions.

Maakaron exclaimed, “It’s truly incredible how much can change in just a year. In 2022, the Lions weren’t even slated to have a primetime game, but now they’re kicking off the NFL schedule against the formidable Kansas City Chiefs. This marks a significant moment for Detroit, as their dedicated efforts to transform their image and culture have finally paid off. The team will have the opportunity to showcase themselves to a nationwide audience, capturing the attention of the entire NFL world as they embark on their rebuilding journey at the start of the new season.”

Lions to play Thursday games with Packers

According to reports, the Detroit Lions are set to face the Green Bay Packers in two Thursday games.

In Week 4, one of the primetime games for Amazon’s Thursday Night Football will be held at Lambeau Field.

On November 23, in Week 12, Detroit will have the opportunity to host the Packers for their annual Thanksgiving Day game at Ford Field.

Lions have four primetime games in 2025-24 NFL Season

In the upcoming season, Detroit will enjoy significant national television coverage with an impressive lineup of four primetime games on their schedule.

  • The first week of the season will take place on September 7th in Kansas City.
  • Green Bay game on September 28 marks Week 4.
  • Week 8: Facing off against Las Vegas on October 30th.
  • December 30th: Away game against Dallas, Week 17

The upcoming Week 8 will witness the Lions hosting a Monday Night Football game for the first time since the 2018 season. Additionally, this occasion marks their return to having at least four primetime games, which hasn’t happened since the 2017 NFL season.

Lions favored in 12 of 17 games for 2025-24 season

There is a considerable amount of excitement surrounding the upcoming season of the Detroit Lions, and it appears that oddsmakers share the sentiment.

In 12 out of their 17 games this season, Detroit is expected to start as the favored team.

Despite being considered a significant underdog with a +6.5 point spread in the opener against Kansas City, the Lions are only considered underdogs in these other games.

  • In Baltimore, the score for Week 7 is +2.
  • The line for Week 10 at L.A. Chargers is +2.5.
  • Minnesota: +1 in Week 16
  • In the Dallas game during Week 17, the point spread is +2.5.

The listed over/under for Detroit’s regular season wins is 9.5.